Table 8.

Factors for poor OS [7,9,10,12,27,45,46,52,55,56,57,59,60,61,62,63,64,65,67,68,69,70,72,82,83]. * only the abstract was available. KPS: Karnofsky performance status.

	Positive CEA level	Low KPS	Extracranial Metastases	Multiple BM	Age	Location of CRC	Others	Score
Thurmaier et al. (2020)			Liver
Quan et al. (2020)	x		x		x			x
Mo et al. (2020)	x		x	x	x			x
Boysen et al. (2020)							N2
Jin et al. (2020) *				x	x
Rades et al. (2020)								x
Muzaffar et al. (2019) *						x
Lu et al. (2019)		x		x
Imaizumi et al. (2019)		x		x			History of chemotherapy
Quan et al. (2019)		x	x
Taylor et al. (2019) *			Liver
Kim B. et al. (2018) *								x
Roussile et al. (2018)			Lung	x			PDL1+
Duan et al. (2018)			Bone	x	x
Yang L. et al. (2018)			x			x	Pathology
Del Carpio Huerta et al. (2018)			x			x
Berghoff et al. (2017) *						x
Sun et al. (2016) *		x		x
Nieder et al. (2016)								x
Roussile et al. (2016) *				x
Karivedu et al. (2015) *		x		x
Gu et al. (2015)			x	x
Chang et al. (2015) *			x				KRAS mutation
Berghoff et al. (2013) *				x		x
Noura et al. (2012)	x		x