Table 4:
TASTE extracted 5 phenotypes from the HF dataset. Red indicates the static features; Dx_ indicates diagnoses; Rx_ indicates medication; The phenotype names are provided by the cardiologist.
| P1. Hypertensive Heart Failure: | Weight |
|---|---|
| dx_Essential hypertension [98.] | 0.804074 |
| Rx_Calcium Channel Blockers | 0.752547 |
| Rx_ACE Inhibitors | 0.648243 |
| Rx_Beta Blockers Cardio-Selective | 0.439681 |
| Rx_Angiotensin IIReceptorAntagonists | 0.230808 |
| Rx_Thiazides andThiazide-Like Diuretics | 0.221251 |
| Static_Non_Hispanic | 0.411001 |
| Static_female | 0.264393 |
| Static_white | 0.263096 |
| Static_Smk_NO | 0.25793 |
| Static_Alchohol_No | 0.239262 |
| P2. Atrial Fibrillation (AF): | Weight |
| dx_Cardiac dysrhythmias [106.] | 0.621756 |
| Rx_Coumarin Anticoagulants | 0.482428 |
| dx_Heart valve disorders [96.] | 0.428493 |
| Static_white | 0.216603 |
| Static_age_greater_80 | 0.20026 |
| Static_Non_Hispanic | 0.191727 |
| Static_male | 0.163882 |
| Static_Alchohol_yes | 0.157758 |
| Static_Smk_Quit | 0.132414 |
| P3. Obesity-induced Heart Failure: | Weight |
| dx_Other back problems | 0.439425 |
| Rx_Opioid Agonists | 0.36535 |
| dx_Intervertebral disc disorders | 0.33781 |
| Rx_Central Muscle Relaxants | 0.326111 |
| dx_Other nervous system symptoms and disorders | 0.22293 |
| Static_white | 0.133696 |
| Static_Static_Severely_obese | 0.110279 |
| Static_age_between_70_79 | 0.107631 |
| P4. Cardiometablic Driving Heart Failure: | Weight |
| dx_Diabetes mellitus without complication [49.] | 0.58191 |
| Rx_Biguanides | 0.075524 |
| Rx_Diagnostic Tests | 0.044592 |
| Rx_Sulfonylureas | 0.041006 |
| Rx_Insulin | 0.031447 |
| Rx_HMG CoA Reductase Inhibitors | 0.027469 |
| dx_Esophageal disorders [138.] | 0.022313 |
| Static_Severely_obese | 0.223931 |
| Static_Alchohol_No | 0.205342 |
| Static_Smk_NO | 0.149338 |
| Static_male | 0.128847 |
| Static_Non_Hispanic | 0.124907 |
| Static_age_between_60_69 | 0.119808 |
| P5. Severe Coronoary Heart Disease: | Weight |
| dx_Coronary atherosclerosis and other heart disease | 0.495272 |
| Rx_Platelet Aggregation Inhibitors | 0.434221 |
| Rx_Nitrates | 0.333018 |
| dx_Heart valve disorders [96.] | 0.230577 |
| Rx_Alpha-Beta Blockers | 0.225503 |
| dx_Peripheral andvisceral atherosclerosis [114.] | 0.124041 |
| Rx_Beta Blockers Cardio-Selective | 0.121939 |
| Static_male | 0.324708 |
| Static_Smk_Quit | 0.190111 |
| Static_white | 0.117237 |
| Static_Overweight | 0.116107 |
| Static_Non_Hispanic | 0.10634 |