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The stability of enasidenib in rat plasma (n = 6, mean ± SD).
| Added (ng/mL) | Room temperature, 2 h | Autosampler 4 °C, 4 h | Three freeze-thaw | -20°C, 4 weeks | ||||
|---|---|---|---|---|---|---|---|---|
| RSD (%) | RE (%) | RSD (%) | RE (%) | RSD (%) | RE (%) | RSD (%) | RE (%) | |
| 2.5 | 7.01 | -3.53 | 6.45 | 1.35 | 6.02 | -1.00 | 4.45 | 1.07 |
| 250 | 7.07 | 2.26 | 5.38 | -1.59 | 5.44 | 1.85 | 5.18 | -0.55 |
| 750 | 1.99 | -0.42 | 2.54 | 0.33 | 1.63 | 0.18 | 1.26 | -0.31 |
