TABLE 2.
MICs of vancomycin and erythromycin in various genetic backgrounds containing an empty pBAD24 vector or the cloned wild-type or mutant yciM gene
| Strain name | Relevant genotype | MIC (μg/ml) of: |
|
|---|---|---|---|
| Erythromycin | Vancomycin | ||
| RAM3212 | ΔtonB (pBAD24) | 64–96 | 128 |
| RAM3213 | ΔtonB (pBAD-yciM) | 64–96 | 128 |
| RAM3214 | ΔtonB yejM1163 (pBAD24) | 6 | 4 |
| RAM3215 | ΔtonB yejM1163 (pBAD-yciM) | 3 | 1.5 |
| RAM3207 | ΔtonB yejM1163 yciM-L95R (pBAD24) | 64–96 | >128 |
| RAM3208 | ΔtonB yejM1163 yciM-L95R (pBAD-yciM) | 4 | 2 |
| RAM3209 | ΔtonB yejM1163 yciM-L95R (pBAD-yciM-L95R) | 96 | >128 |