FIG 7.

Analysis of virions from the sera of HBV-infected patients by CsCl density gradient fractionation. Serum samples from HBV-infected patient 3 (genotype A [gtA]) (A), patient 4 (gtB) (B), patient 10 (gtC) (C), and patient 12 (gtD) (D) were fractionated by CsCl gradient ultracentrifugation. The virion particles in the fractions were analyzed by native agarose gel electrophoresis. HBV DNA and core protein were detected, as described in the legend to Fig. 6, using the indicated NTD- or CTD-specific MAbs. The direction of centrifugation (top to bottom) is indicated.