TABLE 1.
MAb | Peptide | Peptide sequencec | HBc/eAg residues | Epitope residues |
---|---|---|---|---|
1D8 | 36 | ATWVGVNLEDPASRD | 69 to 83 | 75 to 83 (immunodominant loop) |
37 | VGVNLEDPASRDLVV | 72 to 86 | ||
38 | NLEDPASRDLVVSYV | 75 to 89 | ||
39 | DPASRDLVVSYVNTN | 78 to 92 | ||
7E9 | 6 | TVQASKLCLGWLWGM | −14 to 1 | −10 to 5 (unique precore sequence) |
7 | ASKLCLGWLWGMDID | −11 to 4 | ||
8 | SKLCLGWLWGMDIDPa | −10 to 5 | ||
9 | SKLCLGWLWGMDIDPb | −10 to 5 | ||
10 | CLGWLWGMDIDPYKE | −7 to 8 | ||
11 | WLWGMDIDPYKEFGA | −4 to 11 |
N-terminal biotin tag.
C-terminal biotin tag.
Boldface letters denote residues within the respective epitope.