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. 2021 Jan 13;95(3):e01695-20. doi: 10.1128/JVI.01695-20

TABLE 1.

Summary of overlapping peptides that bound to MAb 1D8 or 7E9

MAb Peptide Peptide sequencec HBc/eAg residues Epitope residues
1D8 36 ATWVGVNLEDPASRD 69 to 83 75 to 83 (immunodominant loop)
37 VGVNLEDPASRDLVV 72 to 86
38 NLEDPASRDLVVSYV 75 to 89
39 DPASRDLVVSYVNTN 78 to 92
7E9 6 TVQASKLCLGWLWGM −14 to 1 −10 to 5 (unique precore sequence)
7 ASKLCLGWLWGMDID −11 to 4
8 SKLCLGWLWGMDIDPa −10 to 5
9 SKLCLGWLWGMDIDPb −10 to 5
10 CLGWLWGMDIDPYKE −7 to 8
11 WLWGMDIDPYKEFGA −4 to 11
a

N-terminal biotin tag.

b

C-terminal biotin tag.

c

Boldface letters denote residues within the respective epitope.