Attachment of VLPs to human intestinal tissue after enzymatic removal of the α1,2 fucose group. UEA-I lectin staining without (A) and with (B) fucosidase treatment was performed as a control to confirm cleavage of the α1,2 fucose group. Upon 1,2α-fucosidase treatment, no attachment of GII.4 was observed (C and D). Attachment of GII.3, GII.6, GII.17 (2005, 2014, and 2015), and GIX was reduced (represented by GII.17 2005 staining [E and F]). Attachment of GI.3, GI.6, and GIV.1 was unchanged (represented by GI.6 staining [G and H]). Magnification, 10×.