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. 2021 Feb 17;45(1):35–41. doi: 10.3906/kim-2008-35

Table.

TBinding affinities in kcal/mol of five molecules on three different target proteins.

Binding affinities (kcal/mol) Favipiravir Hydroxychloroquine Remdesivir Lopinavir Ritonavir
SARS-CoV-2RBD –5.1 –4.2 –4.9 –6.9 –6.4
SARS-CoV-2 Mpro-ac –5.4 –5.9 –7.5 –7.5 –6.8
SARS-CoV-2 Mpro –5.7 –5.2 –5.5 –6.6 –6.4
hFURac –5.1 –5.2 –7.0 –6.8 –6.8
hFUR –6.0 –6.0 –6.6 –8.0 –6.9