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. Author manuscript; available in PMC: 2021 Sep 1.
Published in final edited form as: Clin Cancer Res. 2020 Dec 1;27(5):1391–1398. doi: 10.1158/1078-0432.CCR-20-2891

Figure 2. Morphology-based CTC subtypes and survival analysis.

Figure 2.

A) Unsupervised clustering using digital pathology features clustered CTCs into 5 subtypes (A–E) with distinct cell morphology (see Methods). B) Kaplan-Meier curves at baseline and C2D1 with CTC subtypes using a cutoff of 1 cell detected in one mL of blood.