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. Author manuscript; available in PMC: 2022 Mar 5.
Published in final edited form as: Eur J Med Chem. 2020 Nov 25;213:113047. doi: 10.1016/j.ejmech.2020.113047

Figure 4.

Figure 4.

PET-[18F]7b experiments in transgenic mice expressing hM3Dq. Time-uptake curves in baseline (panel A) and blocking studies (blocker – 7d) (panel C, blocker dose = 0.1 mg/kg; panel D, blocker dose = 0.5 mg/kg). Data: mean SUV ± SD (n=3). SUV = standardized uptake value in the mouse striatum (STR), cortex (CTX) and cerebellum (CB). Target-to-non-target ratio versus time (panel B)