Figure 4. Tertiary lymphoid aggregates in PDACs.
A. Hematoxylin and eosin stain of representative untreated PDAC (unvaccinated) and PDAC following vaccine therapy (vaccinated) were shown. Peritumoral and intratumoral lymphoid aggregates were circled in green in lower magnitude images. Selected regions with lymphoid aggregates were also shown in higher magnitude. B. Comparison of the density of intratumoral lymphoid aggregates in PDACs between each two of three arms.