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. 2021 Mar 2;11:4993. doi: 10.1038/s41598-021-83905-7

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Reconstruction of the skull base with an autogenous in situ bone flap. (A,B) Preoperative contrast-enhanced MRI of the sellar region indicated that the tumor was to the right, and the structure of the optic nerve was unclear. (C) Formation of the autogenous in situ bone flap intraoperatively. (D) Autogenous in situ bone flap for skull-base reconstruction. (E,F) Three months after the EEEA, MRI of the sellar region indicated that the tumor had totally resected, and that the optic nerve, pituitary stalk and pituitary gland were intact. (G,H) Three months after surgery, CT of the skull base indicated that the bone flap was well restored, and the osseous anatomic structure of the skull base had been restored.