Table 1.
Characteristics of subjects: demographics, retinopathy of prematurity characteristics, and associated morbidities of prematurity.
| Parameters | Patient group | |
|---|---|---|
| No or mild ROP | Severe ROP | |
| No. of infants | 42 | 58 |
| Birth weight (g), mean ± SD | 995 ± 247 | 744 ± 256 |
| Gestational age (weeks), mean ± SD | 27.6 ± 2.0 | 25.2 ± 2.0 |
| Gender, male (%) | 16 (38) | 31 (53) |
| Race/ethnicity (%) | ||
| Non-Hispanic White | 100 | 100 |
| Lowest zone, no. of eyes (%) | ||
| Never Developed | 72 (86) | 0 (0) |
| Zone I | 0 (0) | 30 (26) |
| Zone II or III | 12 (14) | 86 (74) |
| Highest stage of ROP, no. of eyes (%) | ||
| Stage 0 | 72 (86) | 0 (0) |
| Stage 1 | 2 (2) | 0 (0) |
| Stage 2 | 10 (12) | 24 (21) |
| Stage 3 | 0 (0) | 92 (79) |
| Worst plus disease category, no. of eyes (%) | ||
| Plus | 0 (0) | 57 (49) |
| No plus | ||
| Pre-plus | 0 (0) | 35 (30) |
| Normal | 84 (100) | 24 (21) |
| AP-ROP, No. of eyes (%) | 0 (0) | 24 (21) |
| Associated morbidities of prematurity and management | ||
| BPD (chronic lung disease) (%) | 11 (26) | 40 (69) |
| IVH (%) | ||
| None | 36 (85) | 36 (62) |
| Grade I–II | 3 (7) | 14 (24) |
| Grade III–IV | 3 (7) | 8 (14) |
| Sepsis, overall (%) | 5 (12) | 29 (50) |
| Bacterial (%) | 3 (7) | 26 (45) |
| Fungal (%) | 0 (0) | 2 (3) |
| Unknown type (%) | 2 (5) | 1 (2) |
| NEC, surgical (%) | 1 (2) | 10 (17) |
+Two sample test of proportion.
*Student two-sample T-test.
^Fisher exact table test.
ROP retinopathy of prematurity, BPD bronchopulmonary dysplasia, IVH intraventricular hemorrhage, NEC necrotizing enterocolitis.