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. 2021 Mar 2;11:4986. doi: 10.1038/s41598-021-84445-w

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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ROC curves for urinary 22(R)-hydroxycholesterol, 25-hydroxycholesterol, and 27-hydroxycholesterol. Receiver operating characteristic (ROC) curves for urinary 22(R)-hydroxycholesterol (A), 25-hydroxycholesterol (B) and 27-hydroxycholesterol (C) were obtained by plotting sensitivity against 1-specificity. Sensitivity and specificity were calculated using the results from 14 patients with biliary atresia and 10 with non-biliary atresia cholestatic controls. Areas under ROC curves are shown with 95% confidence intervals.