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. 2021 Mar 2;11:154. doi: 10.1038/s41398-021-01275-0

Table 1.

Demographic characteristics at baseline and follow-ups (FU) 1, 2, and 3.

Overalla
n = 2684
Baselinea
n = 803
FU1a
n = 739
FU2a
n = 651
FU3a
n = 491
p-valueb
Age at scan (years)

17.58 (2.73)

[12.02–25.07]

16.21 (2.52)

[12.02–21.96]

17.30 (2.49)

[12.99–22.93]

18.29 (2.46)

[13.98–23.98]

19.32 (2.49)

[14.92–25.07]

<0.001
Sex >0.9
 F 1380 (51%) 412 (51%) 381 (52%) 332 (51%) 255 (52%)
 M 1304 (49%) 391 (49%) 358 (48%) 319 (49%) 236 (48%)
Race
 African-American/Black 310 (12%) 96 (12%) 87 (12%) 73 (11%) 54 (11%)
 African-American and Caucasian 29 (1.1%) 9 (1.1%) 8 (1.1%) 8 (1.2%) 4 (0.8%)
 Asian 210 (7.8%) 64 (8.0%) 59 (8.0%) 51 (7.8%) 36 (7.3%)
 Asian Pacific Islander 4 (0.1%) 1 (0.1%) 1 (0.1%) 1 (0.2%) 1 (0.2%)
 Asian and White 74 (2.8%) 21 (2.6%) 20 (2.7%) 19 (2.9%) 14 (2.9%)
 Caucasian/White 2024 (75%) 600 (75%) 555 (75%) 491 (75%) 378 (77%)
 Native American/American Indian 7 (0.3%) 3 (0.4%) 2 (0.3%) 2 (0.3%) 0 (0%)
 Native American and Caucasian 5 (0.2%) 2 (0.2%) 1 (0.1%) 1 (0.2%) 1 (0.2%)
 None 6 (0.2%) 2 (0.2%) 2 (0.3%) 1 (0.2%) 1 (0.2%)
 Pacific Islander 12 (0.4%) 4 (0.5%) 3 (0.4%) 3 (0.5%) 2 (0.4%)
 Pacific Islander and Caucasian 3 (0.1%) 1 (0.1%) 1 (0.1%) 1 (0.2%) 0 (0%)
 SES

16.79 (2.47)

[6.00–20.00]

16.79 (2.49)

[6.00–20.00]

16.83 (2.45)

[6.00–20.00]

16.81 (2.48)

[6.00–20.00]

16.71 (2.45)

[6.00–20.00]

0.8
Family AUD density
 0 2008 (75%) 601 (75%) 554 (75%) 487 (75%) 366 (75%)
 0.5 392 (15%) 117 (15%) 108 (15%) 96 (15%) 71 (14%)
 1 158 (5.9%) 46 (5.7%) 42 (5.7%) 39 (6.0%) 31 (6.3%)
 1.5 72 (2.7%) 22 (2.7%) 19 (2.6%) 17 (2.6%) 14 (2.9%)
 2 45 (1.7%) 14 (1.7%) 13 (1.8%) 10 (1.5%) 8 (1.6%)
 2.5 4 (0.1%) 1 (0.1%) 1 (0.1%) 1 (0.2%) 1 (0.2%)
 3 3 (0.1%) 1 (0.1%) 1 (0.1%) 1 (0.2%) 0 (0%)
 4 2 (<0.1%) 1 (0.1%) 1 (0.1%) 0 (0%) 0 (0%)
Drinking class (Cahalan scale) <0.001
 0 1800 (67%) 642 (80%) 512 (69%) 385 (59%) 261 (53%)
 1 471 (18%) 110 (14%) 122 (17%) 131 (20%) 108 (22%)
 2 106 (3.9%) 12 (1.5%) 19 (2.6%) 32 (4.9%) 43 (8.8%)
307 (11%) 39 (4.9%) 86 (12%) 103 (16%) 79 (16%)
Baseline trauma (# of events) >0.9
 0 1029 (38%) 305 (38%) 286 (39%) 251 (39%) 187 (38%)
 1 887 (33%) 265 (33%) 239 (32%) 218 (33%) 165 (34%)
 2 508 (19%) 154 (19%) 144 (19%) 121 (19%) 89 (18%)
 3 181 (6.7%) 56 (7.0%) 49 (6.6%) 42 (6.5%) 34 (6.9%)
 4 79 (2.9%) 23 (2.9%) 21 (2.8%) 19 (2.9%) 16 (3.3%)
Lifetime marijuana use (days)

26.15 (137.2)

[0–2309]

8.80 (86.3)

[0–1712]

16.78 (103.9)

[0–1738]

32.80 (146.5)

[0–2119]

59.82 (210.7)

[0–2309]

<0.001
Lifetime tobacco use (days)

19.37 (247.6)

[0–10796]

3.11 (36.4)

[0–900]

12.39 (106.4)

[0–1827]

19.80 (169.9)

[0–3656]

55.92 (525.6)

[0–10,796]

<0.001

n (%).

aStatistics presented: mean (SD) [minimum-maximum].

bStatistical tests performed: Kruskal–Wallis test; chi-square test of independence.

Bold values indicates statistical significant p-values (p < 0.05).