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. 2021 Mar 2;7:20. doi: 10.1038/s41531-021-00163-0

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Axial slices (5 mm apart) through the thalamus showing the association between the sub-nuclei volumes and the extent of local deformation in the significant clusters at study entry. Pearson product-moment correlation was performed between sub-nuclei volume and local volume values in the two significant clusters. Pearson’s r-values > ± 0.2 for each side (left thalamus local volume with left thalamus sub-nuclei, and similarly for the right side) are depicted on a single subject thalamus segmentation in MNI space. Inferiorly located nuclei were inversely associated, while medial nuclei were positively associated with the extent of local deformation. AV anteroventral, LD laterodorsal, LP lateral posterior, CeM Central Medial, CL Central Lateral, Pc Paracentral, Pf parafascicular, MDm mediodorsal medial magnocellular, MGN medial geniculate, Re Reuniens, Sg suprageniculate, PuA pulvinar anterior, VAmc Ventral Anterior magnacellular.