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. 2021 Mar 2;8:71. doi: 10.1038/s41597-021-00860-8

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© The Author(s) 2021, corrected publication 2021

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Fig. 6 — (a) The average abundance of Enterococcus is higher in patients who got Enterococcal bloodstream infections (n = 79) than in patients who did not (n = 940), especially in the critical period of two weeks after the transplant (day 0, where ‘Day’ is relative to the nearest allo-HCT transplant). (b) The average abundance of bacteria of the genus Escherichia is higher in patients who got a bloodstream infection by that genus (n = 52) than in patients who did not (n = 967), especially in the critical period of two weeks after the transplant (day 0). (c) The hazard ratio calculated for the risk of bloodstream infection after the patient was detected with an intestinal domination. These analyses were previously done by defining intestinal domination at an abundance threshold of 30% domination^13,23. The results shown here reveal that domination redefined at an abundance threshold as small as 1% still increases the risk of bloodstream infection by Enterococcus. (d) The presence in the stool is even a stronger predictor of bloodstream infection for the case Escherichia, for which even levels of 0.1% have a significant association.