Table 2.

Novel suggestive-significant MacTel loci.

Rsid	Chr	BP	Effect/non-effect allele	EAF cases	EAF controls	Cytoband	Odds ratio	95% CI	P value	P value Eur
rs2120770	1	212509005	C/A	0.179	0.218	q32.3	0.717	0.63–0.82	1.55 × 10−06	9.49 × 10−06
rs1260326	2	27730940	C/T	0.511	0.589	p23.2	0.742	0.66–0.83	1.32 × 10−07	5.67 × 10−07
rs1973480	6	74511980	G/A	0.342	0.295	q13	1.33	1.18–1.5	3.35 × 10−06	3.68 × 10−06
rs2954021	8	126482077	G/A	0.442	0.519	q24.21	0.75	0.67–0.84	2.65 × 10−07	2.28 × 10−07
rs2984814	11	31554964	T/G	0.259	0.325	p13	0.755	0.67–0.85	2.40 × 10−06	1.87 × 10−06
rs11077850	17	74661436	C/T	0.255	0.18	q25.1	1.38	1.21–1.58	1.12 × 10−06	1.58 × 10−06

Novel suggestive-significant MacTel loci. The table presents the most significant SNPs reaching suggestive significance (P < 5 × 10⁻⁶) at each locus. All listed genes are covered by the haplotype (as defined by FUMA, based on linkage disequilibrium using the 1000 Genomes Project Europeans). Chr chromosome number, BP base pairs, EAF effect allele frequency, Eur European-only sample subset. This table is duplicated in Supplementary Data 18.