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Global distribution of APOE4 allele in Homo sapiens. Frequency of ε4 is low (light red regions) and high (dark red regions). The gray color indicates that there are no data available for this country. The geographical map of APOE4 frequency was generated using the package, rworldmapR. State estimates were generated by averaging the frequency of APOE4 allele across the various studies conducted in a specific country.
