Table 3.
Summary of pericarditis medications in all patients during base TP and EP
| Medications | ||||||
| At least 1 | Analgesics | Aspirin | NSAIDs | Colchicine | CS | |
| Idiopathic, active, CRP >1 mg/dL (part 1), n/N (%) | ||||||
| Dose stopped | 6/8 (75.0) | 0/0 | 0/0 | 4/6 (66.7) | 2/8 (25.0) | 3/3 (100.0) |
| Dose decreased | 1/8 (12.5) | 0/0 | 0/0 | 1/6 (16.7) | 0/8 | 0/3 |
| Dose increased | 1/8 (12.5) | 0/0 | 0/0 | 0/6 | 1/8 (12.5) | 0/3 |
| Starting new | 0/11 | 0/11 | 0/11 | 0/11 | 0/11 | 0/11 |
| Idiopathic, active, CRP ≤1 mg/dL (part 2), n/N (%) | ||||||
| Dose stopped | 2/3 (66.7) | 0/0 | 0/0 | 1/1 (100.0) | 1/3 (33.3) | 1/2 (50.0) |
| Dose decreased | 1/3 (33.3) | 0/0 | 0/0 | 0/1 | 0/3 | 1/2 (50.0) |
| Dose increased | 0/3 | 0/0 | 0/0 | 0/1 | 0/3 | 0/2 |
| Starting new | 0/3 | 0/3 | 0/3 | 0/3 | 0/3 | 0/3 |
| Idiopathic, CS-dependent (Part 3), n/N (%) | ||||||
| Dose stopped | 4/5 (80.0) | 0/0 | 0/1 | 2/4 (50.0) | 1/5 (20.0) | 4/5 (80.0) |
| Dose decreased | 3/5 (60.0) | 0/0 | 1/1 (100.0) | 1/4 (25.0) | 1/5 (20.0) | 1/5 (20.0) |
| Dose increased | 0/5 | 0/0 | 0/1 | 0/4 | 0/5 | 0/5 |
| Starting new | 0/5 | 0/5 | 0/5 | 0/5 | 0/5 | 0/5 |
| PPS, active, CRP >1 mg/dL (part 4), n/N (%) | ||||||
| Dose stopped | 0/1 | 0/0 | 0/0 | 0/0 | 0/1 | 0/0 |
| Dose decreased | 0/1 | 0/0 | 0/0 | 0/0 | 0/1 | 0/0 |
| Dose increased | 0/1 | 0/0 | 0/0 | 0/0 | 0/1 | 0/0 |
| Starting new | 0/1 | 0/1 | 0/1 | 0/1 | 0/1 | 0/1 |
| PPS, CS-dependent (part 5), n/N (%) | ||||||
| Dose stopped | 3/3 (100.0) | 0/0 | 0/0 | 0/1 | 0/2 | 3/3 (100.0) |
| Dose decreased | 1/3 (33.3) | 0/0 | 0/0 | 1/1 (100.0) | 0/2 | 0/3 |
| Dose increased | 0/3 | 0/0 | 0/0 | 0/1 | 0/2 | 0/3 |
| Starting new | 0/3 | 0/3 | 0/3 | 0/3 | 0/3 | 0/3 |
CRP, C reactive protein; CS-dependent, corticosteroid dependent; EP, extension period; NSAIDs, non-steroidal anti-inflammatory drugs; PPS, postpericardiotomy syndrome; TP, treatment period.