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. 2021 Feb 17;12:646523. doi: 10.3389/fimmu.2021.646523

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Copyright © 2021 Cheng, Wang, Nie, Cheng, Zhang, Hu and Peng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparison of TREM2 gene expression between normal and tumor tissues (left) and immunohistochemistry images in normal (middle) and tumor (right) tissues. TREM2 protein expression was significantly higher in liver hepatocellular carcinoma (LIHC), colon adenocarcinoma (COAD), head and neck squamous cell carcinoma (HNSC), cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), and breast invasive carcinoma (BRCA) tissues than normal tissues. (A) Liver. (B) Colon. (C) Skeletal muscle. (D) Cervix. (E) Breast. (F,G) Lung. ****P < 0.0001.