Table 1.
Relationship between TREM2 expression and immune cell infiltration in different cancers.
| Cell type | BRCA | CESC | KIRC | LUSC | SKCM | STAD |
|---|---|---|---|---|---|---|
| (P-value/Cor) | (P-value/Cor) | (P-value/Cor) | (P-value/Cor) | (P-value/Cor) | (P-value/Cor) | |
| Memory B cells | ***/−0.11 | **/−0.15 | ***/−0.19 | ***/−0.14 | ***/−0.18 | **/−0.13 |
| Naïve B cells | ***/−0.12 | −0.06 | */−0.11 | −0.04 | **/−0.13 | ***/−0.15 |
| Dendritic cells | ***/−0.09 | **/−0.14 | −0.08 | ***/−0.21 | −0.04 | −0.01 |
| Activated dendritic cells | ***/−0.23 | ***/−0.28 | ***/−0.19 | ***/−0.38 | ***/−0.2 | ***/−0.23 |
| Resting dendritic cells | */0.07 | ***/0.21 | 0.03 | ***/0.19 | */0.1 | ***/0.27 |
| Eosinophils | */−0.06 | ***/−0.24 | */−0.1 | −0.03 | **/−0.12 | 0.03 |
| Lymphocytes | ***/−0.12 | */−0.11 | −0.04 | ***/−0.2 | 0.02 | ***/−0.26 |
| Macrophages | ***/0.11 | ***/0.33 | ***/0.17 | ***/0.31 | */0.09 | ***/0.35 |
| M0 Macrophages | ***/−0.18 | **/−0.15 | 0.07 | −0.06 | −0.08 | −0.06 |
| M1 Macrophages | **/−0.07 | ***/0.38 | 0.05 | */0.11 | ***/0.18 | ***/0.16 |
| M2 Macrophages | ***/0.34 | ***/0.42 | ***/0.23 | ***/0.42 | ***/0.13 | ***/0.45 |
| Mast cells | */0.06 | ***/−0.21 | ***/−0.37 | ***/−0.15 | ***/−0.27 | −0.07 |
| Activated mast cells | 0.03 | ***/−0.23 | 0.03 | ***/−0.18 | **/−0.12 | −0.1 |
| Resting mast cells | 0.05 | 0.06 | ***/−0.41 | 0.03 | ***/−0.22 | 0.04 |
| Monocytes | **/0.07 | −0.07 | ***/−0.21 | 0.07 | 0.04 | 0.01 |
| Neutrophils | ***/0.14 | ***/−0.27 | 0.03 | 0.04 | −0.07 | −0.01 |
| Activated NK cells | −0.03 | −0.03 | −0.06 | ***/−0.13 | ***/0.21 | −0.07 |
| Resting NK cells | **/−0.08 | ***/−0.25 | ***/−0.34 | ***/−0.14 | ***/−0.25 | −0.1 |
| Plasma cells | ***/−0.13 | ***/−0.28 | ***/−0.18 | ***/−0.22 | −0.08 | ***/−0.25 |
| Activated CD4 memory T cells | −0.04 | ***/0.19 | 0.06 | */0.1 | */0.1 | ***/0.15 |
| Resting CD4 memory T cells | 0.04 | −0.11 | ***/−0.15 | ***/0.28 | ***/−0.14 | ***/−0.16 |
| Naïve CD4 T cells | −0.05 | */−0.13 | ***/−0.29 | ***/−0.23 | ***/−0.2 | **/−0.14 |
| CD8T cells | 0 | */0.12 | ***/0.19 | −0.07 | ***/0.24 | **/0.13 |
| Follicular T helper cells | ***/−0.15 | 0.06 | 0.08 | ***/−0.31 | −0.07 | ***/−0.2 |
| Gamma delta T cells | −0.05 | 0.06 | 0.08 | 0.07 | 0.07 | 0 |
| Regulatory T cells | ***/0.12 | ***/0.19 | ***/0.23 | ***/0.17 | ***/0.22 | **/0.14 |
BRCA, breast invasive carcinoma; CESC, cervical squamous cell carcinoma and endocervical adenocarcinoma; KIRC, kidney renal clear cell carcinoma; LUSC, lung squamous cell carcinoma; SKCM, skin cutaneous melanoma; STAD, stomach adenocarcinoma.
*
p < 0.05,
**
p < 0.01, and
***
p < 0.001.