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. 2021 Feb 17;12:634553. doi: 10.3389/fgene.2021.634553

TABLE 2.

Identification of 15 genes by the SMR and HEIDI analysis for vitiligo susceptibility.

Chr Gene Top cis-eQTL bSMR2 Standard Error PSMR3 PHEIDI4
4 PPP3CA rs2583389 0.197 0.043 4.12E-06 7.64E-01
10 CASP7 rs3814231 0.585 0.102 1.03E-08 6.24E-01
11 FADS1 rs968567 −0.470 0.099 2.00E-06 3.09E-01
11 FADS2 rs968567 −0.63 0.138 4.35E-06 5.87E-01
15 HERC2 rs2016277 0.511 0.078 6.12E-11 2.50E-01
16 SPATA2L1 rs648548 −0.824 0.169 1.07E-06 3.95E-02
16 DEF8 rs8063761 −1.790 0.326 3.90E-08 1.27E-01
19 IRF3 rs7251 −0.366 0.070 1.42E-07 2.56E-02
22 TEF rs9611565 −1.099 0.208 1.30E-07 1.23E-01
12 SUOX rs7302200 −0.866 0.128 1.30E-11 2.10E-01
14 GZMB rs2236337 −0.269 0.044 1.22E-09 1.38E-01
16 CDK101 rs77651727 0.566 0.108 1.73E-07 4.29E-01
20 ASIP rs62209647 −0.750 0.134 2.30E-08 4.09E-01
12 RPS26 rs1131017 0.192 0.025 2.54E-14 2.77E-02
21 UBASH3A rs1893592 −1.14641 0.203846 1.87E-08 2.42E-01

1Two genes were newly identified and marked in bold. 2The estimated effect size of gene expression on vitiligo from the SMR method. 3P-value from the SMR test. 4P-value from the HEIDI test.

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