Table 3.
Relationship between TMB index and clinicopathological characteristics of lung ASC.
| Characteristics | Numbers of patients (percentage) | TMB (cutoff = 10) | p value | |
|---|---|---|---|---|
| Low | High | |||
| Age | 0.58 | |||
| <70 | 15 (71.4%) | 11 | 4 | |
| ≥ 70 | 6 (28.6%) | 4 | 2 | |
| Sex | 0.63 | |||
| Male | 11 (52.4%) | 8 | 3 | |
| Female | 10 (47.6%) | 7 | 3 | |
| Smoking history | 0.30 | |||
| Smokers | 7 (33.3%) | 4 | 3 | |
| Non-smokers | 14 (66.7%) | 11 | 3 | |
| Pathological stage | 0.03 | |||
| I-II | 12 (57.1%) | 11 | 1 | |
| III | 9 (42.9%) | 4 | 5 | |
| Tumor size (cm) | 0.31 | |||
| ≤ 3 | 7 (33.3%) | 6 | 1 | |
| > 3 | 14 (66.7%) | 9 | 5 | |
| Lymph node | 0.03 | |||
| N0 | 12 (57.1%) | 11 | 1 | |
| N1-N2 | 9 (42.9%) | 4 | 5 | |
| TP53 mutation | 0.59 | |||
| w/t | 8 (38.1%) | 6 | 2 | |
| With | 13 (61.9%) | 9 | 4 | |
| EGFR mutation | 0.27 | |||
| w/t | 11 (52.4%) | 9 | 2 | |
| With | 10 (47.6%) | 6 | 4 | |