Table 6.

Association between adherence to chronic polytherapy and symptom onset (IH-AMI vs OH-AMI), sociodemographics and clinical characteristics

Category	Subcategory	OR	95% CI	P value
Symptom onset of AMI	OH-AMI	1.00	–	–
	IH-AMI	0.54	0.47 to 0.62	<0.001
Gender of patient	Male	1.00	–	–
	Female	0.75	0.71 to 0.79	<0.001
Age group (years)	(18–54)	1.00	–	–
	(55–64)	1.12	1.03 to 1.22	0.007
	(65–74)	0.98	0.90 to 1.07	0.618
	(75–84)	0.67	0.61 to 0.73	<0.001
	(85+)	0.40	0.35 to 0.44	<0.001
Renal disease	No	1.00	–	–
	Yes	0.58	0.53 to 0.64	<0.001
Sinoatrial bradycardia	No	1.00	–	–
	Yes	0.83	0.64 to 1.08	0.171
Asthma	No	1.00	–	–
	Yes	0.51	0.37 to 0.69	<0.001
ST-elevation AMI	No	1.00	–	–
	Yes	1.48	1.40 to 1.56	<0.001
Ongoing concomitant treatments in the 6 months before index admission (no of distinct group of drugs)	(0–1)	1.00	–	–
	(2–4)	1.05	0.98 to 1.13	0.147
	(5–7)	0.92	0.84 to 1.00	0.055
	(8–10)	0.90	0.81 to 0.99	0.046
	(10+)	0.73	0.64 to 0.82	<0.001
E-B drugs use in the 6 months before index admission (at least one prescription)	No	1.00	–	–
	Yes	1.57	1.47 to 1.67	<0.001
Mental disorders	No	1.00	–	–
	Yes	0.72	0.63 to 0.82	<0.001

AMI, acute myocardial infarction; E-B, evidence based; IH-AMI, in-hospital acute myocardial infarction; OH-AMI, out of hospital acute myocardial infarction.