Table 1.
Group 1 (G1) Men (n=2397) |
Group 2 (G2) Premenopausal women (n=517) |
Group 3 (G3) Postmenopausal women (n=2294) |
P value G1 versus G2 |
P value G1 versus G3 |
P value G2 versus G3 |
|
Age, years | 64.1±11.2 | 45.1±4.2 | 66.5±8.8 | <0.001 | <0.001 | <0.001 |
BMI, kg/m2 | 23.3±3.0 | 22.3±3.6 | 22.5±3.3 | <0.001 | <0.001 | 0.631 |
Smoking | ||||||
Current | 600 (25.1%) | 40 (7.7%) | 67 (2.9%) | <0.001 | <0.001 | 0.007 |
Ex | 1204 (50.3%) | 73 (14.1%) | 97 (4.2%) | <0.001 | <0.001 | <0.001 |
Drinker | 1869 (78.2%) | 316 (61.1%) | 866 (37.8%) | <0.001 | <0.001 | <0.001 |
Glucose, mg/dL | 100.7±17.8 | 90.9±9.4 | 96.3±12.3 | <0.001 | <0.001 | <0.001 |
TC, mg/dL | 198.7±32.9 | 199.2±31.2 | 215.4±31.6 | 1.000 | <0.001 | <0.001 |
LDL-C, mg/dL | 115.2±29.6 | 114.2±28.5 | 126.7±28.7 | 1.000 | <0.001 | <0.001 |
TGs, mg/dL | 100 (71 to 146) | 68 (50 to 94) | 89 (67 to 123) | <0.001 | <0.001 | <0.001 |
HDL-C, mg/dL | 56.3±13.8 | 67.8±14.7 | 62.8±14.9 | <0.001 | <0.001 | <0.001 |
Non HDL-C, mg/dL | 142.4±32.6 | 131.4±31.2 | 152.5±31.3 | <0.001 | <0.001 | <0.001 |
TC/HDL-C | 3.7±1.0 | 3.1±0.8 | 3.6±0.9 | <0.001 | <0.001 | <0.001 |
SdLDL-C, mg/dL | 34.1 (24.8 to 46.5) | 23.0 (16.8 to 30.5) | 31.2 (23.5 to 41.8) | <0.001 | <0.001 | <0.001 |
SdLDL-C/LDL-C | 0.32±0.14 | 0.22±0.08 | 0.29±0.12 | <0.001 | <0.001 | <0.001 |
Data are expressed as mean±SD, %, and median (25th percentile, 75th percentile). P values were assessed in one-way analysis of variance and post hoc pairwise comparison (Bonferroni).
BMI, body mass index; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; non HDL-C, non high-density lipoprotein cholesterol; sdLDL-C, small dense low-density lipoprotein cholesterol; TC, total cholesterol; TGs, triglycerides.