Table 1.
Severe asthmatics (SA) | Non-severe asthmatics (NSA) | Healthy subjects (HS) | |
---|---|---|---|
(n) | 14 | 18 | 14 |
Age | 47 | 38 | 43 |
Gender F/M | 8/6 | 10/8 | 8/6 |
Atopic to Der p1 | 14 | 18 | 0 |
FEV1 baseline (%) | 47.7*# | 91.6 | 107.1 |
FEV1 max (%) | 66.4* | 98.7 | – |
Cluster | 4–5 | 1–2 | – |
WBC (g/l) | 8.1 | 6.7 | 6.7 |
NE (%) | 56.3 | 55.6 | 55.7 |
LIMF (%) | 26.4 | 32.4 | 33.6 |
MO (%) | 8.4 | 7.7 | 7.5 |
EOS (%) | 7.9 | 3.6 | 2.6 |
BASO (%) | 1 | 0.7 | 0.6 |
HGB (g/dl) | 14.3 | 14.2 | 13.8 |
PLT (g/l) | 275.9 | 260.8 | 262.7 |
CRP (mg/l) | 4.3 | 2.5 | 2.2 |
Glucocorticoids use | High | low | n.a |
FEV1: forced expiratory volume; WBC: white blood cells; NE: neutrophils; LIMF: lymphocytes; MO: monocytes; EOS: eosinophils; BASO: basophils; HGB: hemoglobin; PLT: platelets; CRP: C reactive protein.
P < 0.05 in comparison to non-severe asthmatics.
P < 0.05 in comparison to healthy subjects.