Table 1.
Baseline characteristics of advanced chronic liver disease patients in the RH7 registry, March 16, 2020 (N = 1 091)
| Variable | Median/count | Range/proportion |
|---|---|---|
| Age | 57 | 19–83 |
| Females | 427 | 29.14% |
| Males | 664 | 60.86% |
| Etiology of ACLD: | ||
| Alcoholic liver disease | 751 | 68.84% |
| Autoimmune (AIH, PBC, PSC) | 109 | 9.99% |
| Viral (HBV, HCV) | 102 | 9.35% |
| Other | 147 | 13.47% |
| Unknown | 84 | 7.70% |
| Scoring systems: | ||
| MELD score | 16 | 6–88 |
| Child-Pugh-Turcotte score | 9 | 5–20 |
| Liver frailty index | 3.35 | 1.69–6.84 |
| Mortality | ||
| 1-year mortality | 430 | 39.37% |
| Yearly registrations | ||
| 2014 | 70 | 6.42% |
| 2015 | 165 | 15.12% |
| 2016 | 191 | 17.51% |
| 2017 | 151 | 13.84% |
| 2018 | 224 | 20.53% |
| 2019 | 256 | 23.46% |
| 2020 (as of March 16th, 2020) | 34 | 10.54% |
| N = 1000* | ||
| Chronic decompensation | 529 | 52,9% |
| Acute decompensation | 398 | 39,8% |
| N = 1091** | ||
| ACLF 1 | 56 | 5.13% |
| ACLF 2 | 41 | 3.75% |
| ACLF 3 | 25 | 2.29% |
ACLD advanced chronic liver disease (cirrhosis); ALD alcohol associated liver disease; HBV hepatitis B virus; HCV hepatitis C virus; AIH autoimmune hepatitis; PBC primary biliary cholangitis; PSC primary sclerosing cholangitis; MELD model for end-stage liver disease; CTPS Child-Turcotte-Pugh score; ACLF acute on chronic liver failure; LFI liver frailty index
*Electronic and paper files of these 1000 patients were double-checked per protocol by one investigator (D.J.)
**Data on remaining 91 patients are straight registry uploads