Table 2.
Age‐ and sex‐standardized prevalence rates of diabetes, prediabetes, and impaired glucose metabolism according to parental history of diabetes in the overall cohort and subpopulations stratified by gender and age
| Prevalence of diabetes, % (95% CI) | Prevalence of prediabetes, % (95% CI) | Prevalence of impaired glucose metabolism, % (95% CI) | |
|---|---|---|---|
| Overall cohort | |||
| FH0 | 8.59 (8.08–9.12) | 15.54 (14.82–16.29) | 24.13 (23.29–24.98) |
| PH | 12.56 (10.24–15.32) † | 12.85 (10.63–15.46) | 25.41 (22.29–28.80) |
| MH | 15.86 (13.66–18.34) † | 15.27 (13.04–17.81) | 31.13 (28.06–34.38) † , ‡ |
| FH2 | 29.81 (21.29–40.02) † | 20.98 (13.60–30.95) | 50.80 (41.39–60.15) † |
| Males | |||
| FH0 | 9.36 (8.61–10.16) | 16.24 (15.19–17.35) | 25.60 (24.37–26.87) |
| PH | 17.65 (13.64–22.54) † | 13.01 (9.76–17.14) | 30.66 (25.66–36.17) |
| MH | 17.64 (14.09–21.86) † | 17.19 (13.55–21.57) | 34.83 (29.66–40.39) † |
| FH2 | 33.37 (19.90–50.23) † | 27.42 (15.07–44.59) | 60.79 (46.29–73.60) † |
| Females | |||
| FH0 | 7.83 (7.16–8.57) | 14.85 (13.88–15.87) | 22.68 (21.56–23.84) |
| PH | 7.13 (5.38–9.38) | 12.68 (9.91–16.08) | 19.81 (16.49–23.60) |
| MH | 14.11 (11.61–17.05) † , ‡ | 13.39 (10.94–16.28) | 27.50 (24.12–31.16) † , ‡ |
| FH2 | 26.28 (17.21–37.94) † | 14.58 (8.40–24.10) | 40.86 (30.36–52.27) † |
| Age <45 years | |||
| FH0 | 3.40 (3.02–3.83) | 10.42 (9.67–11.21) | 13.82 (12.99–14.69) |
| PH | 8.42 (6.10–11.53) † | 11.88 (9.30–15.05) | 20.30 (16.84–24.27) † |
| MH | 9.51 (7.50–11.99) † | 13.77 (10.98–17.13) † | 23.28 (19.80–27.18) † |
| FH2 | 26.19 (15.43–40.82) † | 20.33 (11.32–33.80) | 46.52 (33.63–59.90) † |
| Age ≥45 years | |||
| FH0 | 14.65 (13.69–15.68) | 21.53 (20.29–22.82) | 36.18 (34.78–37.61) |
| PH | 21.17 (16.38–26.91) † | 14.87 (10.97–19.85) † | 36.04 (30.16–42.37) |
| MH | 27.79 (23.32–32.76) † | 18.10 (14.71–22.08) | 45.90 (40.84–51.04) † , ‡ |
| FH2 | 33.61 (21.42–48.45) † | 21.66 (11.23–37.68) | 55.27 (42.17–67.68) † |
Prevalence estimates for diabetes and prediabetes, as well as for impaired glucose metabolism, were calculated and weighted to represent the total population of Chinese adults (aged ≥20 years) on the basis of Chinese population data from 2006 and the study sampling scheme. The differences in the prevalence rates between the groups with different family history patterns were tested using the PAIRWISE procedure in SUDAAN software. P < 0.05 is considered statistically significant.
CI, confidence interval; FH2, both parents affected with diabetes.
Significant difference from negative parental history of diabetes (FH0) within the certain subpopulation.
Significant difference between maternal history of diabetes only (MH) and paternal history of diabetes only (PH) within the certain subpopulation.