Table 2. Factors Associated With Premature Discontinuation of I/Q.

Factor	Premature discontinuation, No./total No. (%)a	OR (95% CI)	P value	AOR (95% CI)b	P value
Age, y
≥60	17/136 (12.5)	1 [Reference]	NA	1 [Reference]	NA
50-59	39/200 (19.5)	1.7 (0.9-3.1)	.09	1.9 (0.9-3.6)	.07
40-49	42/234 (18.0)	1.5 (0.8-2.8)	.17	1.8 (0.9-3.5)	.09
<40	81/385 (21.0)	1.9 (1.1-3.3)	.03	2.5 (1.3-4.8)	.01
Gender
Male	121/721 (16.8)	1 [Reference]	NA	1 [Reference]	NA
Female	56/220 (25.5)	1.7 (1.1-2.4)	.004	1.8 (1.2-2.7)	.01
Transgender or other	2/14 (14.3)	0.8 (0.2-3.7)	.81	0.4 (0.1-2.0)	.26
Race/ethnicity
White	43/217 (19.8)	1 [Reference]	NA	1 [Reference]	NA
Black	52/178 (29.2)	1.7 (1.0-2.7)	.03	1.7 (1.0-2.9)	.045
Latinx	63/432 (14.6)	0.7 (0.5-1.1)	.09	0.9 (0.5-1.5)	.94
Asian or Pacific Islander	8/76 (10.5)	0.5 (0.2-1.1)	.07	0.7 (0.3-1.6)	.36
Multiethnic, other, or unknown	13/52 (25.0)	1.3 (0.7-2.7)	.41	1.4 (0.6-3.2)	.39
Living situation
Home, apartment, RV, or trailer	30/270 (11.1)	1 [Reference]	NA	1 [Reference]	NA
Homeless
Sheltered	43/276 (15.6)	1.5 (0.9-2.4)	.13	1.7 (0.9-3.3)	.13
Unsheltered	76/192 (39.6)	5.2 (3.3-8.4)	<.001	4.5 (2.3-8.6)	<.001
Congregate living setting or SRO	17/140 (12.1)	1.1 (0.6-2.1)	.76	1.3 (0.7-2.7)	.42
Other or unknown	13/77 (16.9)	1.6 (0.8-3.3)	.18	1.2 (0.5-2.9)	.68
Referral source
Outpatient	21/96 (21.9)	1 [Reference]	NA	1 [Reference]	NA
Hospital	84/341 (24.6)	1.2 (0.7-2.1)	.58	1.1 (0.6-2.0)	.75
Homeless service provider or shelter	23/158 (14.6)	0.6 (0.3-1.1)	.14	0.5 (0.3-1.1)	.10
Surveillance or field testing	12/106 (11.3)	0.5 (0.2-1.0)	.05	0.7 (0.3-1.7)	.48
Other	24/146 (16.4)	0.7 (0.4-1.3)	.29	0.6 (0.3-1.2)	.13
Missing	15/108 (13.9)	0.6 (0.3-1.2)	.14	0.5 (0.2-1.1)	.09
COVID-19 status
COVID-19 diagnosis	47/438 (10.7)	1 [Reference]	NA	1 [Reference]	NA
PUI	89/358 (24.9)	2.8 (1.9-4.0)	<.001	1.5 (0.9-2.5)	.09
Close contact	37/141 (26.2)	3.0 (1.8-4.8)	<.001	2.6 (1.5-4.6)	.001
None of the above	2/5 (40.0)	5.5 (0.9-34.0)	.06	4.0 (0.6-29.0)	.17
Missing	4/13 (30.8)	3.7 (1.1-12.5)	.04	4.8 (1.1-21.7)	.04
Elixhauser medical conditionc,d
No	97/583 (16.6)	1 [Reference]	NA	1 [Reference]	NA
Yes	63/274 (23.0)	1.5 (1.0-2.1)	.03	1.4 (0.9-2.2)	.17
Elixhauser mental health disorderd,e
No	110/654 (16.8)	1 [Reference]	NA	1 [Reference]	NA
Yes	50/203 (24.6)	1.6 (1.1-2.4)	.01	1.0 (0.6-1.6)	.89
Elixhauser substance use disorderd,f
No	104/639 (16.3)	1 [Reference]	NA	1 [Reference]	NA
Yes	56/218 (25.7)	1.8 (1.2-2.6)	.002	0.8 (0.05-1.4)	.42
Jail stay in past yeard
No	131/772 (17.0)	1 [Reference]	NA	1 [Reference]	NA
Yes	29/85 (34.1)	2.5 (1.6-4.1)	<.001	1.6 (0.7-2.3)	.39

Abbreviations: AOR, adjusted odds ratio; COVID-19, coronavirus disease 2019; I/Q, isolation and quarantine; NA, not applicable; OR, odds ratio; PUI, persons under investigation; RV, recreational vehicle; SRO, single-room occupancy hotel.

^aN = 955 (excludes patients elevated to a higher level of care and discharges for administrative and safety reasons).

^bModel adjusted for calendar week of referral.

^cElixhauser medical condition was defined as having 2 or more diagnosis codes in the current and past 2 fiscal years in medical records and included rheumatic arthritis, neurologic disorders, paralysis, cancer, kidney failure, liver disease, peptic ulcer disease, hypothyroidism, weight loss, obesity, diabetes, fluid and electrolyte disorders, chronic pulmonary disease, pulmonary circulation disorder, peripheral vascular disease, hypertension, congestive heart failure, valvular disease, cardiac arrhythmias, coagulopathy, blood loss anemia, deficiency anemia, and AIDS or HIV.

^dData not shown for records unmatched to administrative data.

^eElixhauser mental health disorder was defined as having 2 or more diagnosis codes in the current and past 2 fiscal years in medical records and included psychoses and depression.

^fElixhauser substance use disorder was defined as having 2 or more diagnosis codes in the current and past 2 fiscal years in medical records and included alcohol or drug use.