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. 2021 Jan 20;10(3):386. doi: 10.3390/jcm10030386

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Comparison of the number of bone biomarkers in sera of ligature-induced periodontitis. (A) Serum concentrations of NTx-1 as a bone resorption marker. (B) Serum concentrations of osteocalcin as a bone formation marker. Data are presented as the mean ± SD from six or twelve rats per group. * p < 0.05 compared with control. NS indicates no significant differences. Control; group of administration of distilled water for 20 days (n = 6), GLY admin.; group of oral administration with 60 mg/kg of GLY extracts for 20 days (n = 12).