Table 4 -. Functional classes identified for the 447 differentially expressed proteins between the male and female breast tumors (COSMIC v. 86 and MSigDB v. 6.2).
Functional class | Gene symbol |
---|---|
Tumor suppressors | ATP1A1, DNM2, FBLN2, FH, NDRG1, PPP2R1A, PTPN6, SDHB |
Oncogenes | ATP1A1, CALR, CD74, COL1A1, CTNNB1, HNRNPA2B1, HSP90AA1, KTN1, LCP1, MSI2, MSN, MYH11, NONO, SEPT9, TNC, TOP1 |
Protein kinases | EIF2AK2, PRKDC, TRIM28, TWF1 |
Transcription factors | CAND1, CRIP2, TNNB1, NO1, HMGB2, ILF2, ILF3, MYBBP1A, PURA, SSRP1, TRIM28 |
Cytokines and growth factors | CTSG, MIF, OGN, TNC |
Cell differentiation markers | ANPEP, CD36, CD44, CD74, ICAM1, LAMP2, MRC2, SLC3A2, SLC4A1 |