Table 6 -. Main signaling pathways according to the enriched KEGG pathways (p<0.05) from the differentially expressed proteins between the male and female breast tumors (DAVID v. 6.8).
Signaling pathway | Gene symbol |
---|---|
EGFR receptor signaling pathway | AGR2 |
I-kappaB kinase/ NF-kappaB signaling | CD36, HACD3 |
MAPK signaling pathway | HSPA2 |
Nitric oxide mediated signal transduction | CD36, THBS1 |
p53 signaling pathway | THBS1 |
PI3K-Akt signaling pathway | THBS1, TNC, TNXB |
Rac protein signal transduction | HACD3 |
Rho protein signal transduction | HACD3 |
TFG-beta signaling pathway | DCN, THBS1 |
Wnt signaling pathway | CACYBP, PFN1, SLC9A3R1 |