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Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Membrane protein incorporation into a nanodisc. Detergent (black micelle)-solubilized membrane protein (blue) is incubated with a mixture of membrane scaffold protein (MSP; green) and detergent-solubilized lipids (tan). Nanodisc assembly is initiated after detergent removal.