Table 1.

Prediction on the effect of mutations (Y268C, Y268N and Y268S) on PfCytb-ISP protein stability using VAPOR and DynaMut. The tools define ΔΔG > 0 as stabilizing and ΔΔG < 0 as destabilizing.

	Mutations
Prediction Values
	Y268C	Y268N	Y268S
DynaMut (ΔΔG)	−1.06	1.45	1.49
I-Mutant (ΔΔG)	−0.82	−0.98	−1.31
MuPro (ΔΔG)	−0.91	−1.17	−1.37
Stability	Decrease	Decrease	Decrease
PhD-SNP	Disease	-	Disease