Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Feb 23;22(4):2212. doi: 10.3390/ijms22042212

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

An influence of selected KRAB-ZFP TSGs (A) and oncogenes (B) on various cancer-related signaling pathways and phenotypic features in neoplastic cells. The schematic representation demonstrates selected KRAB-ZFPs with oncogenic and TSG properties and their impact on the cellular signaling, apoptosis, response to treatment, proliferation, migration, and invasion of cancer cells, as well as patient survival. Some signaling pathways are yet to be understood. Green arrow—induction, red—inhibition, P—phosphorylation.