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. 2021 Feb 22;22(4):2185. doi: 10.3390/ijms22042185

Figure 2.

Figure 2

Clotting time tests and coagulation factors VIII, XIII and von Willebrand factor are more sensitive to increasing concentrations of cryoprecipitate than fibrinogen concentrate. Increasing concentrations of fibrinogen from either fibrinogen concentrate (Fg-C—blue) or cryoprecipitate (cryo—red) were added to fibrinogen deficient plasma (FDP) and (A) prothrombin time (PT), (B) activated partial thromboplastin time (APTT) and (C) thrombin time (TT) measured using a Sysmex CS-5100 haematology analyser. n = 2. Increasing concentrations of fibrinogen from either fibrinogen concentrate (Fg-C—blue) or cryoprecipitate (cryo—red) were added to fibrinogen deficient plasma (FDP), and (D) FVIII, (E) von Willebrand factor (vWF) and (F) FXIII were measured using a Sysmex CS-5100 haematology analyser. Normal ranges (short dash) and PNP (long dash) are shown by grey dotted lines. Statistical significance is denoted on each relevant graph. Data are represented as mean ± SD. * p < 0.05. n = 2, assays performed in duplicate.