Figure 3.
Increasing fibrinogen concentration in cryoprecipitate and fibrinogen concentrate strongly correlates with rotational thromboelastography (ROTEM) parameters. Increasing concentrations of fibrinogen from either fibrinogen concentrate (Fg-C—blue) or cryoprecipitate (cryo—red) were added to fibrinogen deficient plasma (FDP) and ROTEM tests performed. (A,E) Clotting time (CT), (B,F) maximum clot firmness (MCF), (C,G) clot amplitude at 5 min (CA5) and (D,H) alpha angle parameters are shown for EXTEM and FIBTEM tests, respectively. The r2 of correlation for each parameter is depicted on the graph. Data are represented as mean ± SD. n = 2, assays performed in triplicate.