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. 2021 Feb 22;13(2):694. doi: 10.3390/nu13020694

Table 1.

The main groups of antimicrobial compounds in human milk.

Immunity Cells Macrophages 60%, Neutrophils 25%, Lymphocytes 10%
Antiviral Specific Compounds
Adaptive Immunity Compounds Immunoglobulins sIgA, IgA, IgG, IgM, IgE, IgD
Antiviral Nonspecific Compounds
Cytokines IL-1b, IL-2, IL-4, IL-5, IL-6, IL-8, IL-12, IL-13, IL-16, IL-18, IL-10, IFNg, TNFa, G-CSF, M-CSF, GM-CSF, TGFb1 and -2, sCD14
Innate Immunity Agents Complement, Chemotactic Factors, Interferon, α-Fetoprotein, Mannose Binding Lectin, β-Defensin-1
Antiadherence substances: Oligosaccharides, Mucins, Lactadherin, Glycolipids and Glycosaminoglycans, K-Casein
Milk Fat Globule Antiviral Factors: Fatty acids and Monoglycerides
Carrier Proteins and Enzymes Lactoferrin, Transferrin, Vitamin B-12 binding protein, Steroid binding protein, Leukocyte enzymes, Antiproteases, Platelet-Activating-Factor, Nucleotides, Long-Chain Polyunsaturated Fatty Acids

IL: Interleukin; IFN: Interferon; TNF: Tumor-necrosis factor; G-CSF: Granulocyte colony-stimulating factor; M-CSF: macrophage colony-stimulating factor; GM-CSF: Granulocyte-macrophage colony-stimulating factor; TGF: Transforming growth factor; sCD14: soluble cluster of differentiation 14.