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Molecular role of vitamin C in the transport of uric acid in the proximal renal tubules and in inflammatory process regulation. VC: vitamin C, UA: uric acid, URAT-1: urate transporter 1, SMCT: sodium-coupled monocarboxylate transporter, SVCT: sodium-dependent vitamin C transporter, TXNIP: thioredoxin-interacting protein, NF-κB: nuclear factor kappa-light-chain-enhancer of activated B cells, NLRP3 INF: NLR family pyrin domain containing 3 inflammasome.
