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. 2021 Feb 21;13(2):333. doi: 10.3390/v13020333

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

The three-dimensional structure models for these candidate mosaic proteins, based on the computer-guided homology modeling method. Mosaic sequences were submitted to the SWISS-MODEL server to construct the protein structure. We used PyMOL software to visualize the model, and then evaluated its quality with QMEAN tool. A, S protein; B, N protein; C, M protein; D, E protein; 1, Merged images of mosaic and nature proteins; 2, Proteins found in circulating virus (with PDB ID: 6NZK (from OC43), 6G13 (from MERS-CoV), 5C8S (from SARS-CoV) and 2MM4 (from SARS-CoV) respectively); 3, Mosaic protein.