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. 2021 Feb 23;13(4):929. doi: 10.3390/cancers13040929

Figure 2.

Figure 2

(A) Contribution of single base substitution (SBS) mutational signatures identified per sample. SBS1 and SBS5 are clock-like signatures. SBS15 and SBS21 are related to DNA MMR deficiency and SBS54 constitutes a sequencing artifact (https://cancer.sanger.ac.uk/cosmic/signatures/SBS/index.tt (accessed on 12 June 2020)). (B) Contribution of small insertions and deletions (ID) mutational signatures identified per sample. ID1 and ID2 are clock-like and DNA MMR deficiency related. ID12 has an unknown aetiology (https://cancer.sanger.ac.uk/cosmic/signatures/ID/index.tt (accessed on 12 June 2020)).