6-AN |
6-aminonicotinamide |
ADCC |
Antibody-dependent cellular cytotoxicity |
α-KG |
α-ketoglutarate |
AKT |
Protein kinase B |
AMP |
Adenosine monophosphate |
AMPK |
AMP-activated protein kinase |
CAR |
Chimeric antigen receptor |
CARKL |
Carbohydrate kinase-like protein |
CAT1 |
Cationic amino acid transporter 1 |
CCR7 |
C-C chemokine receptor type 7 |
cDC |
Conventional dendritic cells |
CEBPB |
CCAAT/enhancer-binding protein beta |
CPT1A |
Carnitine palmitoyltransferase-1A |
CREB |
Cyclic AMP response element-binding protein |
CRS |
Cytokine release syndrome |
CTLA4 |
Cytotoxic T lymphocyte-associated antigen 4 |
DAMP |
Danger-associated molecular pattern |
DC |
Dendritic cell |
DMM |
Dimethyl malonate |
DOG |
2-deoxy-glucose |
ECAR |
Extracellular acidification rate |
ER |
Endoplasmic reticulum |
FAO |
Fatty acid oxidation |
FATP2 |
Fatty acid transport protein 2 |
FBP1 |
Fructose-1,6-bisphosphatase |
G-CSF |
Granulocyte colony-stimulating factor |
GC–MS |
Gas chromatography–mass spectrometry |
GLUT |
Glucose transporter |
GM-CSF |
Granulocyte macrophage colony-stimulating factor |
GSK3β |
Glycogen synthase kinase 3β |
G6PD |
Glucose-6-phosphate dehydrogenase |
HIF-1α |
Hypoxia-inducible factor-1α |
HK1 |
Hexokinase 1 |
HRE |
Hypoxia response element |
IFN |
Interferon |
IFNAR |
Interferon-alpha/beta receptor |
IL |
Interleukin |
iLDNs |
Immature low-density neutrophils |
IKKɛ |
IkB kinase-ɛ |
iNOS |
Inducible nitric oxide synthase |
iRAE |
Immune-related adverse events |
IRG1 |
Immunoresponsive gene 1 |
IRI |
Ischemia reperfusion injury |
KEAP1 |
Kelch-like ECH-associated protein 1 |
LAP |
Liver-enriched activated protein |
LC–MS |
Liquid chromatography–mass spectrometry |
LDHA |
Lactate dehydrogenase A |
LGL |
Large granular lymphocyte |
LKB1 |
Serine/threonine kinase 11 |
LPS |
Lipopolysaccharide |
MCT |
Monocarboxylate transporter |
M-MDSC |
Mononuclear myeloid-derived suppressor cell |
MDSC |
Myeloid-derived suppressor cell |
MHC |
Major histocompatibility complex |
MMP-9 |
matrix metalloproteinase-9 |
MSR1 |
Macrophage scavenger receptor 1 |
mTOR |
Mechanistic target of rapamycin |
NET |
Neutrophil extracellular trap |
NK |
Natural killer |
NLR |
Neutrophil lymphocyte ratio |
NMR |
Nuclear magnetic resonance |
NO |
Nitric oxide |
NOX |
NADPH oxidase |
NRF2 |
Nuclear erythroid factor 2 |
OCR |
Oxygen consumption rate |
ODC |
Ornithine decarboxylase |
OxPHOS |
Oxidative phosphorylation |
PAMP |
Pathogen-associated molecular pattern |
PD1 |
Programmed cell death protein 1 |
PD-L1 |
Programmed death-ligand 1 |
PD-L2 |
Programmed death-ligand 2 |
pDC |
Plasmacytoid dendritic cells |
PEP |
Phosphoenolpyruvate |
PGC-1β |
PPARgamma-coactivator-1β |
PGE2 |
Prostaglandin E2 |
PHD |
Prolyl hydroxylase |
PKB |
Protein kinase B |
PKM2 |
Pyruvate kinase M2 |
PMN-MDSC |
Polymorphonuclear myeloid-derived suppressor cell |
PPAR-γ |
Peroxisome proliferator-activated receptor-γ |
PPP |
Pentose phosphate pathway |
PI3K |
Phosphoinositide 3-kinase |
SCENITH |
Single-cell energetic metabolism by profiling translation |
SCF |
c-Kit-derived ligand |
SDH |
Succinate dehydrogenase |
Sema3A |
Semaphorin 3A |
SLC27 |
Solute carrier family 27 |
SRA |
Scavenger A receptor |
SREBP |
Sterol regulatory element-binding protein |
STAT3 |
Signal transducer and activator of transcription 6 |
STAT6 |
Signal transducer and activator of transcription 6 |
TAM |
Tumor-associated macrophage |
TAN |
Tumor-associated neutrophil |
TBK1 |
TANK-binding kinase 1 |
TGFβ |
Transforming growth factor β |
TIGIT |
T cell immunoreceptor with Ig and ITIM domains |
TLR |
Toll-like receptor |
TME |
Tumor microenvironment |
TNBC |
Triple-negative breast cancer |
VEGF |
Vascular endothelial growth factor |
VSIG4 |
V-set immunoglobulin-domain-containing 4 |