Table 1.
Summary statistics of the samples included in each analysis
| Phenotype | N | %CA | %Fe | Age (±SD) | %APOE ε4 | Cohort | Dataset |
|---|---|---|---|---|---|---|---|
| Aβ42 | 558 | 33.51 | 68.33 | 75.98 (6.47) | 40.04 | K | GWAs |
| Tau | 560 | 33.63 | 51.34 | 76.06 (6.56) | 40.22 | K | GWAs |
| pTau | 553 | 32.73 | 51.18 | 76.85 (7.65) | 40.15 | K | GWAs |
| Amyloid imaging | 420 | 20.95 | 53.57 | 76.25 (6.52) | 37.38 | K | GWAs-WES |
| AD progression | 446 | 100.00 | 57.17 | 75.85 (7.02) | 62.50 | K | GWAs-WES |
| AD risk single variant | 12,372 | 55.95 | 54.84 | 80.79 (8.32) | 30.84 | K-N-A | GWAs-WES |
| AD risk gene based | 10,226 | 55.87 | 54.46 | 81.64 (8.27) | 28.56 | K-N-A | WES |
| Total dataset | 12,372 | 55.95 | 54.84 | 80.79 (8.32) | 30.84 | K-N-A | GWAs-WES |
N, number of samples included; %CA, percentage of cases; %Fe, percentage of females; AGE, average age at onset for cases and average age at last assessment for controls; K, Knight-ADRC; N, NIA-LOAD; A, ADSP; SD, standard error.