Table 3.
Baseline (mean ± SD) | End of week 4 (mean ± SD) |
p value | End of week 8 (mean ± SD) |
p value | |
---|---|---|---|---|---|
Symptoms severity | |||||
Total score | 206.00 ± 70.60 | 176.20 ± 65.30 | 0.220 | 208.00 ± 77.80 | 0.920 |
Abdominal pain | 32.10 ± 21.50 | 19.40 ± 24.90 | 0.018 | 30.60 ± 32.30 | 0.894 |
Number of days having pain | 31.60 ± 30.80 | 10.00 ± 13.70 | 0.003 | 23.1 ± 33.4 | 0.472 |
Abdominal distension/tightness | 36.30 ± 30.20 | 40.00 ± 33.70 | 0.260 | 36.90 ± 23.80 | 0.800 |
Satisfaction of bowel habits | 50.50 ± 29.30 | 52.50 ± 26.20 | 0.870 | 59.70 ± 23.60 | 0.230 |
Affect or interfere with life | 55.30 ± 25.00 | 54.40 ± 21.00 | 0.920 | 57.80 ± 27.30 | 0.800 |
Bowel habits | |||||
Maximal number of bowel movements per day | 3.47 ± 1.31 | 2.75 ± 1.18 | 0.026 | 2.44 ± 0.63 | 0.001 |
Passage of mucous | 57.90% | 31.20% | 0.055 | 18.80% | 0.007 |
Hurry/rush to the toilet | 73.70% | 37.50% | 0.015 | 37.50% | 0.019 |
SF-36 | |||||
Physical functioning | 71.93 ± 24.88 | 78.64 ± 20.63 | 0.361 | 80.73 ± 27.67 | 0.245 |
Role-physical | 69.74 ± 36.87 | 67.19 ± 44.46 | 0.860 | 71.87 ± 40.70 | 0.720 |
Bodily pain | 42.11 ± 22.70 | 25.69 ± 16.56 | 0.003 | 30.55 ± 17.45 | 0.068 |
General health | 44.13 ± 13.28 | 51.44 ± 22.59 | 0.220 | 40.38 ± 14.18 | 0.360 |
Vitality | 65.35 ± 12.80 | 66.67 ± 15.21 | 0.830 | 63.54 ± 22.33 | 0.700 |
Social functioning | 52.63 ± 18.47 | 60.71 ± 15.21 | 0.140 | 59.82 ± 9.36 | 0.200 |
Role-emotional | 68.42 ± 34.20 | 68.75 ± 35.42 | 0.890 | 66.67 ± 43.88 | 0.780 |
Mental health | 40.67 ± 22.95 | 42.61 ± 13.97 | 0.840 | 39.77 ± 20.96 | 0.870 |
IBS-SSS irritable bowel syndrome symptom severity score, SF-36 36-item short form health survey