. 2021 Feb 23;6(9):6404–6413. doi: 10.1021/acsomega.1c00008

Table 4. Limits of Detection for Spike Protein Binding to Thiolated 1C,5′ Aptamer on Silver Nanoparticles by Monitoring Changes in SLIPSERS Spectra at 2872 cm⁻¹, and the Concentrations at which these Limits Are Exceeded.

percentile	ΔI_thresh	log₁₀(ΔI_thresh)	log₁₀([spike]) (M)	[spike] (fM)
99	18	1.25	–16.5	0.03
99.9	23	1.37	–15.9	0.13
99.99	28	1.44	–15.5	0.32

Table 4. Limits of Detection for Spike Protein Binding to Thiolated 1C,5′ Aptamer on Silver Nanoparticles by Monitoring Changes in SLIPSERS Spectra at 2872 cm−1, and the Concentrations at which these Limits Are Exceeded.