Table 1.
Sleep architecture and descriptive information across main groups.
| Variable | Antidepressant | Non-medicated | Control | F/χ2 | P Value |
|---|---|---|---|---|---|
| n | 98 | 117 | 148 | — | — |
| Sex distribution (% female) | 64.3 | 67.5 | 45.9 | 14.8 | .001 |
| Age (y) | 43.4 ± 15.0 | 43.7 ± 13.7 | 52.8 ± 15.2 | 17.2 | < .001 |
| BMI (kg/m2) | 29.6 ± 6.6 | 28.9 ± 6.5 | 28.2 ± 5.5 | 1.2 | .310 |
| Sleep architecture (x̅ ± SD) | |||||
| Sleep efficiency (%) | 84.0 ± 11.0 | 84.0 ± 11.9 | 79.8 ± 12.2 | 5.5 | .004 |
| TST (min) | 357.2 ± 60.8 | 357.8 ± 75.0 | 342.9 ± 63.0 | 2.1 | .120 |
| Sleep onset latency (min) | 25.2 ± 24.8 | 17.7 ± 19.1 | 14.7 ± 15.4 | 8.1 | < .001 |
| REM sleep latency (min)a | 208.9 ± 103.9 | 130.2 ± 74.6 | 136.0 ± 81.5 | 26.2 | <.001 |
| NREM sleep (%) | 86.8 ± 7.6 | 83.2 ± 5.8 | 85.5 ± 6.0 | 9.1 | <.001 |
| REM sleep (%) | 13.2 ± 7.6 | 16.8 ± 5.8 | 14.5 ± 6.0 | 9.1 | <.001 |
aThere was no REM sleep noted in 1 individual from the non-medicated group and in 8 in from the antidepressant group. F/χ2 and P values reflect global omnibus statistics (statistics for paired comparisons are reported in the text; please see “Main groups analyses” in the Results section). SD = standard deviation, TST = total sleep time.