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. 2021 Mar 1;17(3):505–513. doi: 10.5664/jcsm.8942

Table 3.

Respiratory indices across main groups.

Control x̅ ± SD Non-medicated x̅ ± SD Antidepressant x̅ ± SD Statistics (F)a
Group Sleep Interaction
AHI (events/h) 6.1** 3.7(*) 2.7(*)
 NREM sleep 10.9 ± 16.7 9.8 ± 13.0 13.8 ± 16.8
 REM sleep 17.9 ± 20.2 20.2 ± 20.3 20.5 ± 22.3
MinSpO2 (%) 2.0 2.4 4.1*
 NREM sleep 89.6 ± 5.2 91.0 ± 3.5 89.4 ± 4.3
 REM sleep 90.0 ± 5.3 90.9 ± 3.7 90.4 ± 4.6
ODI (events/h) 2.9(*) 15.3** 3.5*
 NREM sleep 7.0 ± 12.7 3.6 ± 5.6 8.5 ± 14.3
 REM sleep 13.7 ± 17.9 9.9 ± 11.7 13.2 ± 18.8

aAnalyses were adjusted for age, sex, and BMI. F values are reported for main group effects (differences between mentally healthy control patients, non-medicated patients with depression, and medicated patients with depression), main effects of sleep stages (NREM and REM sleep), and interactions between main groups and sleep stages. Eight individuals in the antidepressant group and 1 in the non-medicated group had no REM sleep. *P ≤ .032, **P ≤ .003, (*)P ≤ .067 (ie, trends). SD = standard deviation.