Table 3.
Control x̅ ± SD | Non-medicated x̅ ± SD | Antidepressant x̅ ± SD | Statistics (F)a | |||
---|---|---|---|---|---|---|
Group | Sleep | Interaction | ||||
AHI (events/h) | 6.1** | 3.7(*) | 2.7(*) | |||
NREM sleep | 10.9 ± 16.7 | 9.8 ± 13.0 | 13.8 ± 16.8 | |||
REM sleep | 17.9 ± 20.2 | 20.2 ± 20.3 | 20.5 ± 22.3 | |||
MinSpO2 (%) | 2.0 | 2.4 | 4.1* | |||
NREM sleep | 89.6 ± 5.2 | 91.0 ± 3.5 | 89.4 ± 4.3 | |||
REM sleep | 90.0 ± 5.3 | 90.9 ± 3.7 | 90.4 ± 4.6 | |||
ODI (events/h) | 2.9(*) | 15.3** | 3.5* | |||
NREM sleep | 7.0 ± 12.7 | 3.6 ± 5.6 | 8.5 ± 14.3 | |||
REM sleep | 13.7 ± 17.9 | 9.9 ± 11.7 | 13.2 ± 18.8 |
aAnalyses were adjusted for age, sex, and BMI. F values are reported for main group effects (differences between mentally healthy control patients, non-medicated patients with depression, and medicated patients with depression), main effects of sleep stages (NREM and REM sleep), and interactions between main groups and sleep stages. Eight individuals in the antidepressant group and 1 in the non-medicated group had no REM sleep. *P ≤ .032, **P ≤ .003, (*)P ≤ .067 (ie, trends). SD = standard deviation.