Table 4.
Respiratory indices across depression subgroups.
| Non-medicated x̅ ± SD | NDRI x̅ ± SD | SSRI x̅ ± SD | Statistics (F)a | |||
|---|---|---|---|---|---|---|
| Group | Sleep | Interaction | ||||
| AHI (events/h) | 0.4 | 1.8 | 4.3* | |||
| NREM sleep | 9.8 ± 13.0 | 7.8 ± 11.2 | 15.2 ± 17.6 | |||
| REM sleep | 20.2 ± 20.3 | 18.3 ± 26.7 | 21.1 ± 21.4 | |||
| MinSpO2 (%) | 3.2* | 0.4 | 4.8** | |||
| NREM sleep | 91.0 ± 3.5 | 91.5 ± 2.2 | 88.9 ± 4.6 | |||
| REM sleep | 90.9 ± 3.7 | 91.6 ± 3.9 | 90.1 ± 4.8 | |||
| ODI (events/h) | 2.8 | 9.3** | 7.2*** | |||
| NREM sleep | 3.6 ± 5.6 | 2.8 ± 2.3 | 9.8 ± 15.6 | |||
| REM sleep | 9.9 ± 11.7 | 12.6 ± 21.3 | 13.3 ± 18.3 | |||
aAnalyses were adjusted for age, sex, and BMI. F values are reported for main group effects (differences between patients with depression taking SSRIs, patients taking NDRIs, and non-medicated patients with depression), main effects of sleep stages (NREM and REM sleep), and interactions between main groups and sleep stages. There was no REM sleep noted in 1 individual in the non-medicated group, 1 in the NDRI group, and 7 in the SSRI group. *P ≤ .041, **P ≤ .009, ***P ≤ .001.