Table 3.
Hematologic and laboratory findings in patients with mild/moderate SARS-CoV-2 infection [Mean value and range (%) from 10 differente studies]
Parameter | Clinical significance | Mild/moderate cases (%) |
Lymphopenia (<1.5 × 109/L) | Defective host response | 47-54% |
Leukocytosis ( >10×109/L) | Bacteria superinfection | 19–30% |
Neutrophilia | Bacterial superinfection, cytokine storm | 1.4 % |
Thrombocytopenia (<100 x 10 9/L) | Consumptive coagulopathy | 4% |
Elevated CRP | Severe viral infection, including viremia | 45.5-56.4% |
Elevated procalcitonin (≥0.25 to <0.5 ng/mL) | Bacterial superinfection | 7% |
Elevated LDH (>245 U/L) | Pulmonary injury/ multiorgan damage | 63% |
Prolonged prothrombin time (> 16 s) | Consumptive coagulopathy | 1.7% |
Prolonged APTT (>37.0 s) | Consumptive coagulopathy | 9.6% |
Elevated D-dimer (>1 μg/L) and/or FDP | Consumptive coagulopathy | 6%, |
Legend: Abbreviations = CRP-C reactive protein; LDH – lactate dehydrogenase; APTT-activated partial thromboplastin time; FDP-fibrin degradation product.